Rectus femoris muscle cross-sectional area measured by ultrasound is associated with postoperative recovery metrics following deceased-donor kidney transplantation
Nicholas Mendez, MD, University of California, San Francisco, San Francisco, CA

Gut microbiota is associated with postoperative delirium in patients
Laura Zhang, MD, PhD, Massachusetts General Hospital/Harvard Medical School, Boston, MA

Ischemic Post-Conditioning Increases Rate of Return of Spontaneous Circulation after Cardiac Arrest in Diabetic Rats  
Matthew Barajas, MD, Vanderbilt University Medical Center, Nashville, TN

Lung entropic hysteresis: The concept of retained energy in mechanically ventilated ARDS patients
Aiman M. Suleiman, MD, MSc, Beth Israel Deaconess Medical Center, Boston, MA
 
The influence of intraoperative opioid administration on postoperative pain and opioid requirements
Laura A. Santa Cruz Mercado, MD, Beth Israel Deaconess Medical Center, Boston, MA

Incidence and Risk Factors of Perioperative Respiratory Adverse Events in Children Undergoing Elective Surgery Employing Logistic Regression and Machine Learning Cluster Analysis
Johnny  Kenth, BSc, MSc, MBBS, FRCA, PG Cert, MSc, MAcadMEd, Royal Manchester Children’s Hospital, Manchester, England

Association of Anesthesiologist Staffing Ratio with Postoperative Morbidity and Mortality
Michael Burns, MD, PhD, University of Michigan, Ann Arbor, MI, United States

CYP2B6 and POR polymorphisms influence metabolism and clinical outcomes of perioperative methadone in children
Senthil Packiasabapathy, MD, Indiana University School of Medicine, Indianapolis, IN, United States

Anesthesia and the gut microbiome: exploring the effects of isoflurane, propofol, and supplemental oxygen in a murine model of general anesthesia
Mara Serbanescu, MD, Johns Hopkins University School of Medicine, Baltimore, MD, United States

The electroencephalographic signature of spinal anesthesia in infants: a multi-center pilot study
Emmett Whitaker, MD, University of Vermont Health, Burlington, VT, United States

Epidemiology of Surgical Site Infection in Spinal Fusion Surgery and Patterns of Discordance with Surgical Antibiotic Prophylaxis: A Retrospective Case-Level Analysis
Dustin R. Long, MD, University of Washington Medicine, Seattle, WA, United States

Unplanned Postoperative Intubation in Infant and Neonatal Surgical Patients: Predictors and Associated Mortality
Lisa Eisler, MD, Columbia University Medical Center, New York, NY, United States

Echocardiographic Assessment using Subxiphoid-only view (EASy) compared to Focused Transthoracic Echocardiography (FoTE) in the perioperative period: A multicenter prospective study
Nibras Bughrara, MD, Albany Medical Center, Albany, NY, United States

Age at Exposure to Anesthesia in Children and Mental Disorder Diagnosis
Caleb Ing, MD, MS, Columbia University, New York, NY, United States

A Randomized Trial of Perioperative Gabapentin to Promote Pain Resolution and Opioid Cessation in a Mixed Surgical Cohort
Jennifer Hah, MD, MS, Stanford University, Stanford, CA, United States

Preoperative factors predict neurocognitive disorder after CABG or PCI in a population-based cohort of older adults
Elizabeth Whitlock, MD, MSc, University of California, San Francisco School of Medicine, San Francisco, CA, United States

Local anesthetics induce an anti-tumoral immune response in vitro and in tumor established in mice
Lucillia Bezu, MD, PhD, Gustave Roussy Cancer Campus, Villejuif, France

Comparison of Intravenous Waveform Analysis to Current Markers for Detection of Hemorrhage in a Rat Model
Matthew Barajas, MD, Vanderbilt University Medical Center, Nashville, TN, United States

Implementation of a Distributed Research Network Virtual Data Warehouse for a Multi-Center Observational Study
Seshadri Mudumbai, MD, Stanford University School of Medicine, Palo Alto, CA, United States

Total Intravenous Anesthesia with a Novel Formulation of Isoflurane Perfluorocarbon-based Nano-emulsion: Safety, Efficacy and Toxicity in Dogs
Behrouz Ashrafi, MD, University of Miami, Miami, FL, United States

Concurrent Surgery and Perioperative Outcomes: A Retrospective Analysis from the Multicenter Perioperative Outcomes Group
Eric Sun, MD, PhD, Stanford University, Stanford, CA, United States

Pharmacological calcium/calmodulin-dependent protein kinase (CaMKII) Inhibition Protects Against Purkinje Cell Damage Following Cardiac Arrest and Cardiopulmonary Resuscitation in Mice
Nidia Quillinan, PhD, University of Colorado Denver, Aurora, CO, United States

Photo-Relaxation: Light Mediated Airway Smooth Muscle Relaxation
Peter Yim, MD, Columbia University, New York, New York

Bitter Taste Receptors in Airway Smooth Muscle Cells of a Cystic Fibrosis Mouse Model
Nicholas M. Dalesio, MD, Johns Hopkins Medicine, Baltimore, Maryland

The Analgesic Effects of Dopamine
Norman E. Taylor, MD, PhD, Massachusetts General Hospital, Boston, MA, United States

Gating of the TREK1 Tandem Pore Potassium Channel, A Molecular Signal Integrator and Anesthetic Target
Paul M. Riegelhaupt, MD, PhD, Weill Cornell Medicine, New York, NY, United States

Isoflurane Discrupts the Development of Dendrites in the Mouse Hippocampus via Activation of the mTOR Pathway
Cyrus Mintz, MD, PhD, John Hopkins Hospital, Baltimore, MD, United States

Pediatric Delierium in Critically Ill Infants and Preschool-aged Children: Validation and Reliability of the Preschool Confusion Assessment Method for the Intensive Care Unit (psCAM-ICU)
Heidi A.B. Smith, MD, MSCi, Vanderbilt University, Nashville, TN, United States

Inflammation Increases Brain Sensitivity to General Anesthetics
Sinziana Avramescu, MD, PhD, FRCPC, Sunnybrook Health Sciences Centre, Toronto, Canada

Specialized Pro-resolving Mediators in a Mouse Model of Postoperative Cognitive Decline
Niccolo Terrando, BsC (hons), Karolinska Institut, Stockholm, Sweden

Optogenetic Stimulation of Dopamine Neurons in the Ventral Tegmental Area
Norman E. Taylor, MD, PhD, Massachusetts General Hospital, Boston, MA, United States

A Novel Strategy to Treat Human Pre-Term Labor – Targeting the TMEM16/Anoctamin Chloride Channel in Human Pregnant Uterus
George Gallos, MD, Columbia University, New York, NY, United States

Switching Microglia to a Neuroprotective Phenotype: A Novel Way to Improve Neuronal Survival After Cardiac Arrest
Ines P. Koerner, MD, PhD, Oregon Health & Science University, Portland, OR, United States

An Engineered Water Soluble Variant of Human MU Receptor
Renyu Liu, MD, PhD, University of Pennsylvania, Philadelphia, PA, United States

Perineural Dexmedetomidine Added to Ropivacaine for Sciatic Nerve Block in Rats Prolongs the Duration of Analgesia by Blocking the Hyperpolarization-Activated Cation Current (Ih Current)
Chad Brummett, MD, University of Michigan Medical School, Ann Arbor, MI, United States

Long-Term Differences in Cognitive and Language Ability After Exposure to Surgery and Anesthesia in Infancy
Caleb Ing, MD, Columbia University College of Physicians and Surgeons, New York, NY, United States

Phase-Locked Acoustic Stimulation Increases Human Thermal Arousal Thresholds during Dexmedetomidine Sedation
Christian Guay, MD, Washington University School of Medicine in St. Louis, St. Louis, MO, United States

Modulation Of Microvascular Blood Flow And Stroke Outcome Via GPR39 in Mice
Yifan Xu, MD/PhD, Oregon Health and Sciences University, Portland, OR, United States

Sustaining the Gains – A 6 Year Follow through of the Impact of a Hospital Wide Patient Safety Strategy on Global and Anesthetic Patient Safety Outcomes
Ming Ann Sim, MBBS, National University Hospital Singapore, Singapore

Derivation, Validation, and Sustained Performance of a Hospital-Wide Elective Surgery Delirium Risk Tool (AWOL-S)
Elizabeth L. Whitlock, MD, MSc, University of California, San Francisco School of Medicine, San Francisco, CA, United States

Weak EEG α-power during general anesthesia as a marker of delirium in the PACU
Matthias Kreuzer, PhD, Emory University, Atlanta, GA, United States

A Novel Association Between High Density Lipoprotein Levels and the Risk of Acute Kidney Injury After Cardiac Surgery
Loren E. Smith, MD, PhD, Vanderbilt University, Nashville, TN, United States

The Relative Effects of Dexmedetomidine and Propofol on Cerebral Blood Flow and Brain Oxygenation: A Noninferiority Study
Michael Kot, MD, Cleveland Clnic, Cleveland, OH, United States

Postoperative Dementia: Role of Anesthesia and APOE4
Katie J. Schenning, MD, MPH, Oregon Health & Science University, Portland, OR, United States

The effect of tidal volume on postoperative respiratory complications is dependent on patients’ respiratory system elastance: A multicenter hospital registry study
Aiman Suleiman, MD, MSc, SPC, Beth Israel Deaconess Medical Center, Boston, MA, United States

Bacterial Sepsis Increases Fibrillary Amyloid Load and Neuroinflammation in a Mouse Model of Alzheimer’s disease Pathology
Jacob Basak, MD, PhD, Washington University School of Medicine in St. Louis, Saint Louis, MO, United States

Response to inhaled anesthetics measured by the Triple Variable Index reveals population-specific patterns of intraoperative hypotension exposure
Michael P. Schnetz, MD, PhD, University of Pittsburgh Medical Center, Pittsburgh, PA, United States

Extracellular miRNAs and Innate Immune Activation Following Polytraumatic Injury in Mice
Andrew O. Suen, MD, University of Maryland, Baltimore, MD, United States

The pro-apoptotic protein BAX is necessary for neuron death associated with exposure to isoflurane general anesthesia in a neonatal mouse model
Andrew Slupe, MD, PhD, Oregon Health and Science University, Portland, OR, United States

Clinical Study of Non-Invasive Venous Waveform Analysis (NIVA) for Prediction of Fluid Responsiveness in Spontaneously Breathing Subjects
Richard B. Boyer, MD, PhD, Massachusetts General Hospital, Boston, MA, United States

Sensitivity to volatile anesthetics predicts postoperative delirium
Bradley A. Fritz, MD, Washington University School of Medicine in St. Louis, St. Louis, MI, United States

Low Molecular Weight Hyaluronan Mediated Inflammation and Airway Hyperresponsiveness in Acid Aspiration Induced Acute Lung Injury in Mice
Weifeng Song, MD, PhD, University of Alabama at Birmingham, Birmingham, AL, United States

Mitochondrial TRPV1 Regulates Endothelial Dysfunction in Diabetes
Nana-Maria Wagner, MD, Stanford University, Stanford, CA, United States

Dexmedetomidine’s Inhibitory Effects on Acetylcholine Release from Cholinergic Nerves in Guinea Pig Trachea: A Mechanism That Accounts for its Clinical Benefit during Airway Irritation
Maya Mikami, MD, PhD, Columbia University College of Physicians and Surgeons, New York, NY, United States

Effects of Race and Common Genetic Variation on Therapeutic Response Disparities in Postoperative Atrial Fibrillation
Nazish K. Hashmi, MB, BS, Duke University Medical Center, Durham, NC, United States

miR-200c Contributes to Injury From Transient Cerebral Ischemia in Mice by Targeting Reelin
Creed M. Stary, MD, PhD, Stanford University, Stanford, CA, United States

Genetic Deletion of the GABAA ∝4 Subunit Leads to Increased Airway Resistance and Inflammation
Gene T. Yocum, MD, Columbia University, New York, NY, United States

Novel Chloride Channel Blockers Relax Airway Smooth Muscle: Potential New Tools to Treat Bronchospasm
Jennifer Danielsson, MD, Columbia University Medical Center, New York, NY, United States

Stimulation of Stimulation of α2-Adrenergic Receptors Antagonizes Isoflurane-Induced Activation of Sleep-promoting VLPO Neurons and Partially Attenuates Anesthetic Hypnosis
Michael R. Chalifoux, MD, University of Pennsylvania, Philadelphia, PA, United States

Anesthetics Interfere With Axon Guidance via a GABAA Receptor Mechanism
Cyrus D. Mintz, MD, PhD, Columbia University Medical Center, New York, NY, United States

Identification and Characterization of a Novel Compound That Protects Cardiac Tissue From hERG-Related, Drug-Induced Arrhythmias
Amanda N. Lorinc, MD, Vanderbilt University, Nashville, TN, United States

Determination of Optimal Blood Pressure for Cardiopulmonary Bypass Based on Near Infra-Red Spectroscopy Autoregulation Monitoring Versus Estimates From Preoperative Blood Pressure
Charles Brown, MD, The John Hopkins University School of Medicine, Baltimore, MD, United States

Inhibition of KCC2 in Mouse Spinal Cord Neurons Leads to Hypersensitivity to Thermal Stimulation
Thomas M. Austin, MD, Vanderbilt University School of Medicine, Nashville, TN, United States

Modulation of the Post-Surgical Hypercoagulable State: Effi cacy of Intravenous Heparin and Possible Implications for Prevention of Organ Failure
Sara S. Cheng, MD, PhD, University of Colorado, Denver, Aurora, CO, United States

Targeted Discovery of a Small-Molecule Inhibitor of the GIRK Channel
Daniel F. Lonergan, MD, University Medical Center, Franklin, TN, United States

Hypothalamic Knockout of Leptin Receptor in a Murine Model Leads to Early Obesity and Diabetes
Laurence Ring, MD, Columbia University, New York, NY, United States

Metabolomic Serotypes of Perioperative Myocardial Infarction Following Cardiac Surgery with Planned Myocardial Ischemia-Reperfusion
Robert Lobato, MD, MS, Duke University Medical Center, Durham, NC, United States

Preoperative and Intraoperative Predictors of 30 Day Cardiovascular Events after Non-Cardiac Surgery
Sachin Kheterpal, MD, MBA, University of Michigan, Ann Arbor, MI, United States

Alpha 2-Noradrenergic Antagonist Administration into the Central Nucleus of the Amygdala Blocks Stress-Induced Hypoalgesia in Awake Behaving Rats
Justin Ortiz, MD, Oregon Health & Science University, Portland, OR, United States

Weak Polar Interactions Confer Albumin Binding Site Selectivity for Haloether Anesthetics
Renyu Liu, MD, Massachusetts General Hospital, Boston, MA, United States

Determination of the EC50Amnesic Concentration of Etomidate and Its Diffusion Profile in Brain Tissue: Implications for In VitroStudies
Claudia Benkwitz, MD, University of Wisconsin, Madison, WI, United States

Over-Transfusion in Pediatric Patients Intra-operatively. A Retrospective Observational Study at a Tertiary Pediatric Hospital.
Timothy Walsh, MD, Boston Children’s Hopsital, Boston, MA, United States

Designing a Novel Manual Communication System for Mechanically Ventilated ICU Patients
Miriam Madsen, Meng, University of Massachusetts, Worcester, MA, United States

Anterior Insula Suppression at Loss of Volitional Behavioural Response
Katie Warnaby, PhD, John Radcliffe Hospital, Oxford, United States

Selective Inhibition of the Calcineurin Interaction Site of TRPV1 Reduces Myocardial Infarct Size by Reducing Mitochondrial Calcium Influx
Eric R. Gross, MD, PhD, Stanford University, Stanford, CA, United States

Intraoperative Normoxia, Oxidative Damage, and Organ Injury following Cardiac Surgery
Frederic T. Billings IV, MD, MSc, Vanderbilt University, Nashville, TN, United States

Training Factors that Modulate Laryngoscopy Learning
Randolph Hastings, MD, PhD, VA San Diego Healthcare System, San Diego, CA, United States

A Network of Discrete Metastable Activity States Mediates Recovery from Isoflurane Anesthesia
Andrew Hudson, MD, PhD, University of California, Los Angeles, Los Angeles, CA, United States

Parasagittal Approach During Interlaminal Lumbar Epidural Steroid Injections is Better in Long-Term Pain Relief and Quality of Life Improvement in Patients with Low Back Pain and Unilateral Radicular Pain
N. Nick Knezevic, MD, PhD, Advocate Illinois Masonic Medical Center, Chicago, IL, United States

The Role of the preBötzinger Complex in Opioid-Induced Respiratory Depression is Age-Dependent
Astrid G. Stucke, MD, Medical College of Wisconsin, Milwaukee, WI, United States

Chitosan Surface Coating for Biomaterials: Unique pH-Dependent Swelling and Antibacterial Properties
David Eckmann, MD, PhD, University of Pennsylvania, Philadelphia, PA, United States

The Difficult Airway Response Team (DART): An Intervention to Manage In-Hospital Airway Emergencies
Lynette Mark, MD, Oregon Health & Science University, Portland, OR, United States

The Mu Opioid Receptor Regulates Lewis Lung Carcinoma Tumor Growth and Metastasis
Jonathan Moss, MD, PhD, University of Chicago, Chicago, IL, United States

Genomewide Association Study (GWAS) of Ventilator-Induced Lung Injury (VILI) Using Dense Single Nucleotide Polymorphism (SNP) Maps in Mice
Li-Ming Zhang, MD, University of Pittsburgh, Pittsburgh, PA, United States